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Download scientific diagram | Representative images of the Napkin-ring sign assessed by coronary computed tomography angiography (CCTA) in a 55-year-old man with worsening-type chest pain. A.


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Recently, several small studies suggested that a certain morphological pattern in CT, a hyperdense ring-like structure surrounding a hypodense center, described as "napkin-ring" sign, (NRS) is associated with advanced coronary plaque as defined by the AHA classification [9], [10], [11].


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The napkin-ring sign (NRS) represents a ring-like attenuation of the non-calcified portion of the coronary lesion and has a high specificity (96-100%) for the identification of thin cap.


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The authors speculated whether this appearance could indicate the presence of deep micro-calcifications, intramural thrombus, intraplaque contrast enhance-ment due to the presence of neovascularization, or represent a large central lipid core surrounded by. The cross-sectional CT images show a coronary plaque with napkin-ring-like.


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The napkin-ring sign is described on CCTA in cross-sectional images of coronary arteries as a central low-attenuation area surrounded by an open ring area of high attenuation, having a high specificity and positive predictive value for the presence of advanced lesions.


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Our report suggests that the napkin-ring sign, which is considered a CT signature of high-risk coronary atherosclerotic plaque, may be caused by the difference in attenuation between a lipid-rich necrotic core (corresponding to the central low attenuation area in CT) and fibrous plaque tissue (corresponding to the rim of high CT attenuation).


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The incidence of a napkin ring sign was around ten times greater in those found to have ACS than those without (32.4% vs 3.2%). However, the napkin ring sign is not a particularly common finding on CTCA. In the SCOT-HEART trial the napkin ring occurred in 0.3% (78 of 26,525) of vessel segments analysed (7).


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Recently, several small studies suggested that a certain morphological pattern in CT, a hyperdense ring-like structure surrounding a hypodense center, described as "napkin-ring" sign, (NRS) is associated with advanced coronary plaque as defined by the AHA classification [9], [10], [11].


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Objectives Carotid atherosclerosis plays an essential role in the occurrence of ischemic stroke. This study aimed to investigate whether a larger burden of napkin-ring sign (NRS) plaques on cervicocerebral computed tomography angiography (CTA) increased the risk of acute ischemic stroke (AIS). Methods This retrospective, single-center, cross-sectional study enrolled patients with NRS plaques.


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The napkin-ring sign was defined by the following criteria: 1) the presence of a ring of high attenuation around certain coronary artery plaques; and 2) attenuation of the ring presenting higher than those of the adjacent plaque and no >130 Hounsfield units.


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The napkin ring, occasionally called a Christening bangle, was originally used to identify the napkins of a household between weekly wash days.